For this reason, many affected women and men avoid sexual activity, tight undergarments, and such activities as riding bicycles. For children with lichen sclerosus affecting the perianal region, constipation may be among the first signs of the presence of the disease. Fissures, cracks, and purplish patches (ecchymoses) appear frequently. An eruption of bluish-white pimples, either separate or joined together, containing a central depression or a black plug of hard skin occurs. a thyroid protein (thyroglobulin), or certain cells that line the walls of organs. Some scientists believe that a genetic predisposition to lichen sclerosus exists. Lichen sclerosus is much more likely to affect males that have not been circumcised than males that have been.
Females are six times as likely to be affected as are males.
The lesions consist of bluish-white flat patchy areas on the inside of the cheeks and/or palate. Autoimmune disorders arise when the body’s natural defenses against “foreign” or invading organisms (e.g., antibodies) begin to attack healthy tissue for unknown reasons.